A plumbed eyewash shall be provided at all work areas where formaldehyde solutions in concentrations greater than or equal to 0.1% are handled. Laboratories–Design and construction. 8. California Radiation Control Regulations, Title 17  Supply system air should meet the technical requirements of the laboratory work and the requirements of the latest version of ASHRAE, Standard 62, Ventilation for Acceptable Indoor Air Quality. Good practices stem from industry standards and/or the judgement/knowledge of Standard University’s EH&S professionals. Safety Exits. 4. TH4652.G85 2013 727 ' .5–dc23 2012048262 Printed in the United States of America 10 9 8 7 6 5 4 3 2 1 . National Institutes of Health Design Requirements Manual (December 12, 2016) Section Title I, “Employment,” Sec. It is important to segregate laboratory and non-laboratory activities because (1) the handling and storage of hazardous materials inherently carries a higher risk of exposure and injury; (2) the egress path from a lab desk to an exit should not require movement through a more hazardous zone; and (3) it is prohibited to store, consume food, apply make-up or chew gum in areas where hazardous materials are used and/or stored. This is also the recommendation of the World Health Organization (WHO) as well as the major Biosafety cabinet manufacturers. The design of the laboratory building must incorporate adequate additional facilities for food storage/consumption and personal hygiene tasks. 7. Construction of the venting duct should be equal to the rating of the cabinet. It’s a place for you to share your vision of how we could develop standards better and how they could add greater value to Australian society by being delivered in more user focused ways. Since these requirements can impact the design of a project, Environmental Health and Safety (EH&S) prepared this EH&S Laboratory Design Guide to aid the campus community with planning and design issues. Proper operation of fume hoods must be demonstrated by the contractor installing the fume hood prior to project closeout. Highly toxic flammable or toxic flammable gases when not stored in gas cabinets, exhausted enclosures or gas rooms. Title 8, 3317, Illumination. As a general rule, airflow should be from areas of low hazard, unless the laboratory is used as a clean or sterile room. Hoods should be labeled to show which fan or ventilation system they are connected to. All cabinets must be NSF listed, UL approved, and installed in accordance with the manufacturer’s requirements. Air exhausted from laboratory work areas shall not pass unducted through other areas. e) Hoods used for radioactivity should have sashes with horizontal sliding glass panels mounted in a vertical sash. Such equipment shall meet all applicable requirements. When the BSC is hard-ducted or connected by thimble unit to the ventilation system adequate space must be provided so as not to interfere with air flow. The relative emphasis to be placed on standards of performance and on … Chains or metal straps at the bottom and top one third of each cylinder provides protection against tipping and falling. Seismic shelf lips (3/4 inch or greater), sliding doors, or mesh nets are examples. A fire or explosion in a fume hood located adjacent to a path of egress could trap someone in the lab. Laboratories working with biological agents must also notify the Health and Safety Executive when category HG2, HG3 and HG4 agents are used on the premises for the first time. changing existing building ventilation systems). If a 120-volt outlet or receptacle is present within 6 feet of an eyewash or shower, it shall be equipped with a Ground Fault Circuit Interrupter (GFCI). Portable hoods often do not meet the regulatory airflow requirements. Any other type of fan orientation increases the fan work load and increases the risk of exhaust emission re-entrainment. 4. If such facilities are deemed absolutely necessary, the facility must be under the direction, control and authority of a single principal investigator, who shall be accountable for maintaining the facility in a safe and orderly manner. Fume hood interior surfaces shall be constructed of corrosion resistant, non-porous, non-combustible materials such as type 316 stainless steel, and should be smooth and impermeable, with rounded corners. In general, a reading of 0.5ms-1 is acceptable for work with hazardous materials, with school fume cupboards requiring higher minimum readings. Most radioisotope projects will need about 10 sq. Wooden and wood finish walls or floors are not appropriate because they can absorb hazardous and/or potentially infectious material, particularly liquids, making decontamination/remediation virtually impossible. Exhaust fans shall be located outside the building at the point of final discharge. Substances identified by the manufacturer or distributor as corrosive or severely irritating to the skin. 3. CDC-NIH Biosafety in Microbiological and Biomedical Laboratories 5th Edition, Section IV – Laboratory Biosafety Level CriteriaSection, Biosafety Level 2 D. Laboratory Facilities (Secondary Barriers) -# 11, Guidelines for Research Involving Recombinant DNA Molecules (NIH Guidelines)  Appendix G-II-B-4. State of California, Department of Health Services, Radiologic Health Branch, Guide for the Preparation of Projects within the “campus site” are covered by the University’s existing Hazardous Waste Generator “permit”. Proper education of the facility users is essential. An adequate supply of make up air (90% of exhaust) should be provided to the lab. 32. The latter will be particularly relevant in a school laboratory. When the hazardous materials stored in laboratories and similar areas used for scientific experimentation or research are not in excess of the tables below and are not otherwise classified as Group B Occupancies, shall conform to the Building Code requirements for Group H, Division 8 (“H-8”) Occupancy. If you own or are... read more, A workplace that lacks worthwhile communication runs the risk of grinding your lab’s gears to a halt, and with... read more, A Guide to Regulations and Planning Permission When Building a Science Laboratory, InterFocus Ltd, Cambridge Road, Linton, CB21 4NN. c)  The interior of all radioisotope hoods must have coved corners to facilitate decontamination. All attempts should be made to neutralize any interferences. Fiberglass also releases toxic smoke when burned. California Radioactive Material License, 0676-43, Stanford University Radiation Safety Manual. When write-up desks are located within the laboratory, they must be at the entrance of the laboratory, with the wet lab benches, fume hoods, biosafety cabinets, and equipment using or storing chemicals, biological materials, and radioactive materials located on the opposite side of the laboratory; this allows laboratory personnel and visitors to enter the laboratory without traveling through the hazardous materials zone of the lab. Chemical fume hood exhaust fans should be connected to an emergency power system in the event of a power failure. 7. Good practice per Stanford University EH&S. 2. 1. CDC-NIH Biosafety in Microbiological and Biomedical Laboratories (BSL 2, D.4)  Air pressure in laboratories and animal care rooms should be negative in relation to the corridor or adjacent non-laboratory areas. Section: Title : Table of Contents: 0-1 Introduction. 6. Portable cryogenic containers are required to be individually secured with a minimum of 1 (one) restraint. Building Occupancy Classification- Occupancy classification is to be based upon an assessment of a projected chemical inventory of the building. A shutoff valve should be located within sight of the connection and clearly marked. Examples and guidance are provided on the ProtectSU website protectsu.stanford.edu. 1. Recommend that solvent storage not be located under the laboratory fume hood, as this is a location where fires are most likely to occur in laboratories. For example, you may opt to incorporate FD60-rated fire safe walls into your lab in place of a more expensive sprinkler system. In practice, lab aisles must be designed wider than 24” so that even with the presence of lab stools and other miscellaneous items, a clearance of 24” is always maintained. The Stanford Laboratory Standard & Design Guide is not “all inclusive.” It does not cover all regulatory issues nor does it cover all design situations. Consult with SU Fire Marshal for design details. You can restrict access by using a standard lock and key, a pin-code entry system or a swipe card entry system. a)  Heated perchloric acid shall only be used in a laboratory hood specifically designed for its use and identified as “For Perchloric Acid Operations.” (Exception: Hoods not specifically designed for use with perchloric acid shall be permitted to be used where the vapors are trapped and scrubbed before they are released into the hood.). However, if the cabinet is not installed properly (e.g., not ducting a Class II, B2 cabinet), then it will not be serviceable. Flammable gases shall not be stored with oxidizing agents. 1. (a)  Design must allow for substances which, when mixed, react violently, or evolve toxic vapors or gasses, or which in combination become hazardous by reason of toxicity, oxidizing power, flammability, explosibility, or other properties, to be separated from each other in storage by distance, by partition, or otherwise, so as to preclude accidental contact between them. 8. If horizontal sashes are used, sash panels (horizontal sliding) must be 12 to 14 inches in width. 2. Laboratory by Earl Walls Associates. Where appropriate, general ventilation systems should be designed, such that, in the event of an accident, they can be shut down and isolated to contain radioactivity. Bench spacing shall be considered and included in specifications and plans. UL listing and EH&S approval assures a minimum level of quality consistent with code requirements and good practice. If the bench abuts a wall, it must be coved or have a backsplash against the wall. Guidance from the HSE states that a minimum allocation of 11m3 is required per person working in a space. 23. All equipment requiring anchoring shall be anchored, supported and braced to the building structure in accordance with CCR Title 24, Part 2, Table 16A-O. When the hazardous materials stored in a control area are not in excess of the amounts specified in the tables below, such storage shall conform to the Building Code requirements for Group B Occupancy. Liquid pools and residue buildup which can result from condensation may create a hazardous condition if allowed to collect. Section 1 of this Guide, General Requirements for Stanford Laboratories, covers all design requirements for Biosafety Level 1 laboratory work areas. the rules that outline the methods that employers must employ to ensure the safety of their employees Are your work surfaces made from easy-to-clean materials. Laboratory Design, Construction, and Renovation: Participants, Process, and Product by National Research Council, Committee on Design, Construction, and Renovation of Laboratory Facilities. IAEA, Safe Handling of Radionuclides  In the event of an emergency, the laboratory may be unsafe to enter. they are in a well protected, well ventilated, dry location, at least 20 feet from highly combustible materials. The decision has been made in accordance with recommendations from numerous agencies. It covers the design, construction, and installation of Flammable Liquid Storage Cabinets; the Guide does not address the proper use of Flammable Liquid Storage Cabinets. research teams, a well-maintained clean room is central to the ongoing success All BSL2 laboratories shall have vacuum lines which are protected with liquid disinfectant traps and high efficiency particulate air (HEPA) filters or filters of equivalent or superior efficiency. It shall be vented outdoors to an approved location or through a flame arrester to a fume hood exhaust system. It covers testing and calibration performed using standard methods, non-standard methods, and laboratory-developed methods. 1. “Safe Handling of Radionuclides”, International Atomic Energy Agency, Safety Series No. The minimum accepted reading will vary slightly depending on your application. The most appropriate location for the plenum is near the exhaust port of the fume hood (i.e., proximal to the hood). Have you allowed for adequate washing facilities, such as an eye bath station? Fire doors should be: The doors may seem a minor consideration when developing a new laboratory, but these need to be subjected to their own rigorous checks. Separate storage for full or empty cylinders is preferred. All furniture must be sturdy. 1. Flow rate and discharge pattern shall be provided in accordance with ANSI Z358.1-2014. Note: The following requirements apply to H-7 occupancies only. j) Each perchloric acid hood must have an individually designated duct and exhaust system. It is left to the discretion of the user of the Guide to include the design feature. Walkways shall be stable, planar, flush, and even to the extent possible. The California Medical Waste Management Act. All labs should be designed to conveniently and safely accommodate the temporary storage of biological, radiological, and chemicals (non-waste and waste) based on laboratory use projections. Different flooring between the office and laboratory zones is desirable, as it can provide a visual cue between the office/write- up desk area of the lab and the area where hazardous materials are used and stored. 2. A system for ensuring safe access would include prohibition on the materials stored on shelves, limitations on the frequency of use, availability of ladders or ladders stands, training on ladders, etc. These bars shall be installed at the back edge of the bench to minimize bench space used. Hood inserts are only permitted for radioactive iodination procedures specifically approved by the Stanford Radiation Safety Officer. 36. Such self-closing doors are to be able to be opened with a minimum of effort as to allow access and egress for physically challenged individuals. in elevators. However, it is the project proponent’s responsibility to provide the necessary information to EH&S for inclusion in the plan. Planning and regulations can seem complicated and daunting, that’s why we’ve put together this guide to meeting all standards and maintaining the highest quality of building work. Such rooms have been permitted with 3 to 4 ACH. Drying ovens shall not be placed under fume hoods. 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